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Low Power Integrated Pumping and Valving Arrays for Microfluidic Systems
Peter A. Krulevitch, William J. Benett, Klint A. Rose, Julie Hamilton, Mariam Maghribi
U.S. Patent 7,025,323 B2
April 11, 2006
Low-power integrated pumping and valving arrays provide a new approach for performing these operations in microfabricated fluidic systems, such as the microchips used in medical diagnostics. Traditional methods that rely on external high-pressure sources do not offer the advantages of miniaturization. Other microfabrication devices are power and voltage intensive and, thus, only function at sufficient pressure to be broadly applicable. This new approach integrates a lower power, high-pressure source with a polymer, ceramic, or metal plug enclosed within a microchannel, analogous to a microsyringe. When the pressure source is activated, the polymer plug slides within the microchannel, pumping the fluid on the opposite side of the plug without allowing fluid to leak around the plug. The plugs also can serve as microvalves.

Solid-Water Detoxifying Reagents for Chemical and Biological Agents
Dennis M. Hoffman, Ing Lap Chiu
U.S. Patent 7,030,071 B2
April 18, 2006
Solid-water reagents for detoxifying chemical and biological agents are formed by coating reagent solutions with small quantities of hydrophobic nanoparticles. When the aerosolized solution is shaken vigorously in the presence of the nanoparticles, a solid powder forms. For example, when hydrophobic fumed silica particles are shaken in one normal concentration of Oxone in aqueous solution at a ratio of about 95 to 5, the silica forms a porous coating of insoluble fine particles around the solution. Chemical and biological agents tend to be hydrophobic. Therefore, when the weakly encapsulated detoxifying solution contacts an agent, the porous coating breaks down. The detoxifying reagent is then delivered directly to the chemical or biological agent, providing maximum concentration at the point it is needed. The solid-water (coated) solution can be blown into contaminated ventilation ducting or other difficult-to-reach sites to detoxify pools of a chemical or biological agent. Once an agent has been detoxified, it can be removed by flushing the area with air or other techniques.

Laser Driven Ion Accelerator
Toshiki Tajima
U.S. Patent 7,030,398 B2
April 18, 2006
This system for accelerating ions optimizes the energy produced by a light source. With the system, an accelerator’s performance can be adjusted by controlling different parameters when constructing the accelerator target, such as the target’s material, thickness, geometry, and surface.

Electronic Unit Integrated into a Flexible Polymer Body
Peter A. Krulevitch, Mariam N. Maghribi, William J. Benett, Julie K. Hamilton, Klint A. Rose, James Courtney Davidson, Mark S. Strauch
U.S. Patent 7,030,411 B2
April 18, 2006
This peel-and-stick electronic system has a silicone body with at least one electronic unit connected to it. The electronic system is produced by providing a silicone layer on a substrate, providing a metal layer on the silicone layer, and providing at least one electronic unit connected to the metal layer.


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UCRL-52000-06-7/8 | July 7, 2006